Interleukin 4 (IL-4) induces B-cell differentiation and survival of chronic lymphocytic leukemia (CLL) cells.MicroRNAs (miRNAs) regulate mRNA and protein expression, and several miRNAs, deregulated in CLL, might play roles as oncogenes or tumor suppressors.We have studied the miRNA profile of CLL, and its response to IL-4, by oligonucleotide Tooth
Abstract Background Systems Biology Markup Language (SBML) is the standard model representation and description language in systems biology.Enriching and analysing systems biology models by integrating the multitude of available data, increases the predictive Tooth Powders power of these models.This may be a daunting task, which commonly requires b
Scientific evidence should form the basis for policy and practice decisions concerning animal welfare.However, cultural attitudes inevitably influence decision-making processes.We conducted a survey of general attitudes towards the welfare of zoo-housed animals, live prey feeding and trust in zoo management in British and Japanese zoo visitors (1,6
Many factors (internal and external) can make a business vulnerable.In the context of the international financial crisis, the firms, and especially the small and mediume enterprises (SMEs) have to face new challenges.Smaller ASANA SMOOTHIE CUBES businesses are particularly prone to financial difficulties as they often lack resources to adapt to the
Abstract Many historic buildings are at serious risk of deterioration due to changes in the moisture content of the soil under the buildings.Based on the typical deterioration problems of the Grand Deliverance Probes Hall and the cultural relics in the hall, this study analyzes and concludes that the main factor affecting the generation and develop